Procedure For Analysis of Water rinsing

1.0 Objective
To define a procedure for analysis of rinsing water samples received from production dept. so as

to as certain the equipments free from previous contamination.
2.0 Scope
Rinsing water samples received from production department at abc Pvt. Ltd.
3.0 Responsibility
3.1 Executive – Quality Control.
3.2 In charge/Head-Quality Control.
4.0 Abbreviations and Definitions
SOP : Standard Operating Procedure
QC : Quality Control
CC NO : Change Control Number
cGMP : Current Good Manufacturing Practice
G : General
5.0 Procedure
5.1 The frequency of analysis of water rinses will be as and when sample is received from production dept.
5.2 Production department will send the intimation along with water rinsing and blank

sample i.e. purified water used for washing.
5.3 The rinsing water will be analyzed by spectrophotometer method.
5.4 The rinsing water will be analyzed by spectrophotometer method.
5.5 Test preparation: water rinsings.
5.6 Blank: Purified water used for washing.
5.7 Determine the absorbance of standard and test preparation using Distilled water as

blank on a UV/Visible Spectrophotometer in the region 200nm-600nm.
5.8 Interpretation: The absorbance of test preparation should not be more than that of

standard preparation when scanned in the above region. If the absorbance of the test

preparation is more than that of the standard, then the washing of the particular equipment

and machinery should be continued till the rinsings show less absorbance than the standard.
5.9 Rinse sample will also analyzed for conductivity and for ph and these both the should

comply as per the limit for purified water.
5.10 Analysis the sample for colour used in previous product manufactured.
5.11 Note: The standard graphs are scanned and maintained for comparison purpose.
5.12 The results of analysis should be filled in the blank report format signed by the analyst and

the group in charge and should be send to production department.
6.0 Forms and Records
6.1 None.
7.0 Distribution
7.1 Master copy – Documentation Cell (Quality Assurance)
7.2 Control copy – Quality Assurance, Quality Control
8.0 History