sop for Laboratory discipline

 

1.0 OBJECTIVE

To lay down the discipline of those persons operating within the quality control laboratory.

2.0 RESPONSIBILITY

Chemist/ Executive

3.0 ACCOUNTABILITY

Manager Q.C

4.0 PROCEDURE

4.1 Laboratory operators must work under supervision unless they have satisfactorily demonstrated their
Competence with respect to the specific operation.

4.2 Analytical Procedure

4.2.1 Familiarize yourself fully with the analytical procedure by reading the SOP before starting the
analysis irrespective how well you know the procedure – there may have been an approved change in
the method since you last performed the analysis.

4.2.2 Perform all analytical procedures exactly according to the approved documented specifications.

4.2.3 Do not change or otherwise modify any analytical procedure without first obtaining the proper
Authorization through the “Change Control Procedure”.

4.2.4 Record all observations on the appropriate works sheet

4.2.5 Calculations must be given in full detail , irrespective how simple they may appear.

4.2.6 Make all entries in clear , legible handwriting , using a ball point pen or ink; (never use a pencil).

4.2.7 Any incorrect entries shall be corrected by striking out the incorrect entry with a single , straight line
such that the original entry is still legible. Do not overwrite on the incorrect entry. Make the correct
entry alongside ; initial and date the correction.

4.2.8 Under no circumstances shall errors be obliterated with “white – out”.

4.2.9 Date and sign all observations and analytical results.

4.2.10 Date and sign original test records ,scans, charts etc. and attach to the analytical report.

4.2.11 All laboratory records shall be independently checked , initialed and dated.

4.3 Reagent Preparation and Standardisation

4.3.1 Prepare all reagents strictly in accordance with the written, approved procedure.

4.3.2 Record all details in the Laboratory Reagent Register , sign and date each entry.

4.3.3 Record full details of the standardization of analytical reagents in the Laboratory Reagent Register,
including the calculation in full . Sign and date the entry.

4.3.4 Label the container of the reagent with the following.

. Name of the reagent
. Date of preparation
. Strength, concentration or normality of the reagent
. Laboratory Reagent Register reference
. Initials of the person who prepared the reagent
. Expiry or use by date

4.3.5 Always use a clean , dry bottle or other appropriate container for each new reagent.

4.3.6 Never re-fill a used bottle for storing reagents, even if used for the same reagent previously.

4.3.7 Always use a new label ; do not amend an existing label for a new reagent.

4.4 Laboratory Instrumentation

4.4.1 Treat all laboratory instruments with care and operate only according to the approved Standard
Operating Procedure.

4.4.2 Keep all instruments covered when not in use.

4.4.3 Clean all spillages on instruments immediately.

4.4.4 Ensure that the equipment has been calibrated before use .Do not use any instrument which has gone
beyond the re-calibration date.

4.4.5 Take care to switch off instruments when not in use.
4.5 Housekeeping

4.5.1 Maintain the work benches in a clean tidy manner at all times.

4.5.2 Clean up any spillages immediately.

4.5.3 Clear away all unused apparatus , place dirty glassware in the place provided ready for washing.

4.5.4 Remove all obstacles from the floor.

4.5.6 Replace all reference books , SOP’s and Laboratory Records in the appropriate storage place
immediately after use. Do not place them lying on the bench when not in use.

4.5.7 Avoid handling noxious or toxic substances in the open laboratory. Use the fume hood provided .

4.5.8 Keep inflammable solvents away from naked flames.

4.5.9 Do not smoke, eat or drink in the laboratory.

5.0 ABBREVIATIONS
nil

6.0 REFERENCES
Nil