master formula record adrenaline tartrate injection


master formula record adrenaline tartrate injection



COMPOSITION : Each ml Contains:
Adrenaline bitartrate 1.0 mg
equivalent to Adrenaline I.P. 1.8 mg
Sodium metabisulphite I.P. 1.0 mg

BATCH SIZE : 100 Litres

SELF LIFE : 1 Year

PACKAGING : 1 ml Amber ampoule


Sr. No. Raw Materials Qty Per ml Overages Total qty per ml Quantity per batch
01. Adrenaline bitartarete 1.8mg 8% 1.94mg 194.4gm
02. Sodium Metabisulphite 1.0mg 1.0mg 100.0gm
03. Disodium EDTA 0.5mg 0.5mg   50.0gm
04. Sodium Chloride 8.0 mg 8.0mg  800.0gm
05. Sodium Hydoxide As per Ph
06. Water for injection q.s. q.s. q.s.


1. Clean all the equipment /containers required for bulk manufacturing with (teepol/liquid soap) rinse it with
tape water and D.M.Water.
2. In the bulk manufacturing area rinsed twice all the above mentioned items with fresh distilled water.
3. Collect 60 litres fresh distilled water in the tank and start nitrogen flushing for 30 minutes.
4. Then add disodium E.D.T.A.,sodium metabisulphite , Adrenaline bitartrate and then add sodium chloride
with continuous sterring.
5. Finally check and adjust the pH between 2.8 to 3.6 with sodium hydroxide.
6. Make up the volume upto 100 litres.

Note – should be kept 3.8 as pH lower on standings.

Product Name : Adrenaline Tartarate Injection

Self life : 1 Year

Colour : Clear, colourless solution.

Contents : 1.10 ml

pH : 2.8 to 3.6

Assay : Adrenaline Bitartrate 1.0mg
Equivalent to Adrenaline I.P. 1.8mg/ml
Limit 87.5 % to 112.5%

• Bulk yield (After filtration) between 98 -100 %.
• After Filling, Sealing and visual Inspection completion the % yield is NLT 95%.

After optical inspection ampoules are kept on labeling machine .


At the start of the batch the printing of the labels should be checked and signed by competent person.

Periodic check has to be done so that the labeled ampoules have a good aesthetic appearance.


master formula record cyproheptadine hcl and tricholine citrate syrup

master formula record l-carnitine injection

master formula record piroxicam injection

master formula record ranitidine injection

master formula record tranexamic acid injection

master formula record tranexamic acid injection

master formula record cetirizine syrup

MFR of sucralfate oral suspension

Master formula record Quinine Sulphate Suspension

MFR of Paracetamol Phenylephrine Hcl Chlorpheniramine Maleate Drops

master formula record paracetamol oral suspension

master formula record ethamsylate 250 mg injection 2 ml

master formula record ofloxacin oral suspension

master formula record Fluconazole Cream

master formula record ondansetron oral solution

MFR of hydroxyzine hydrochloride oral solution

master formula record vitamin D3 drops

master formula record furazolidone oral suspension

MFR of Clobetasol Propionate cream 

master formula record Povidone iodine ointment 5%

MFR of Magaldrate Simethicone and Oxetacaine Suspension

master formula record albendazole oral suspension

master formula record ondansetron injection

master formula record nandrolone decanoate injection

MFR of iron sucrose injection

MFR of diclofenac sodium injection



Leave a Comment

error: Content is protected !!