General Test Procedure Identification by TLC Purpose This procedure is applicable to incoming Raw materials, in process and finished products. Apparatus Thin Layer Chromatographic Plates Micro syringes Micropipettes Calibrated disposable capillaries TLC chamber UV chamber Reagents None Procedure Prepare mobile phase by mixing solvents in the ratio as per given in the individual test. Procedure … Read more
General Test Procedure Identification by HPLC Purpose This procedure is applicable to all incoming Raw materials, In-process and Finished products. Apparatus HPLC Column HPLC Vial Reagents HPLC grade Water HPLC grade chemicals Procedure Compare the retention time of standard and sample in the assay test as mentioned in the assay method. The major peak … Read more
General Test Procedure Identification by IR 1.0 Purpose 1.1 This procedure is applicable to all incoming raw materials. 2.0 Apparatus 2.1 Infrared Spectrophotometer 2.2 Hydraulic Pellet Press 2.3 Lab Oven 2.4 Analytical Balance 3.0 Reagents 3.1 Potassium Bromide spectroscopic grade 3.2 Liquid Paraffin AR grade 3.3 Sodium chloride 4.0 Procedure … Read more
Analysis of Glimepiride and Metformin Hydrochloride (SR) Tablets Description : Take 10 tablets, observed visually & record. Identification As per Assay procedure: Positive test for Glimepiride & Metformin Hydrochloride. Average Weight : Weigh accurately 20 tablets, note down the weight and divide the gross weight by 20 to obtain … Read more
SOP FOR CLEANING OF FLUID BED DRYER When a product is changed, or even if the same product granulation is to be continued after ten batches of the product are completed, the cleaning and assembly process that follows will be followed. A Procedure for product to product changeover Cleaning external surface and plenum Clean … Read more
sop for cleaning of dust exhausts OBJECTIVE It is essential that the processing of each and every batch of any product is designed in such a way that there are no chances of cross contamination. Dust extraction “hood assemblies” being the potential contributors towards the problem of cross contamination, need regular cleaning as per … Read more
CLEANING OF DRY SYRUP POWDER FILLING MACHINE 1. Put off the electric connections. 2. Dismantle the nozzle, hopper, auger and the main shaft and transfer them to the equipment cleaning room. 3. Wash all the parts with hot water and a soap solution (10% soap and 1% disinfectant) ning soft nylon wire brush. 4. … Read more
CLEANING OF DOUBLE CONE BLENDER 1.Caution :Disconnect the equipment from electrical main supply. 2. Set the position of the blender vertical-butterfly valve facing the floor A ) PROCEDURE FOR PRODUCT TO PRODUCT CHANGEOVER 1. Dismantling- a. Remove the safety guard of the blender b. Remove the circular lid and gasket by unclamping wing nuts. … Read more
CLEANING OF CONVENTIONAL COATING PAN Coating pan 1. As soon as the coating operation is over, remove the coated tablets in suitable contains Remove the dry powder from the pan, if any. 2. Pour approximately 20 liters of hot water (80-85 °C) into the pan and allow the pan to r for about 10 minutes. … Read more
Cleaning of capsule inspection cum polishing machine PROCEDURE FOR PRODUCT TO PRODUCT CHANGEOVER 1. Dedusting external surfaces Using cleaned nylon brush and vacuum cleaner. Remove the filter bag of the vacuum can placed below the machine. 2. Dismantling-Remove: a. Hopper assembly with sieves and trays. b. Conveyor belt with guides and slitter guards. … Read more