sop for Spillage Control
1.0 Objective
To lay down a procedure for spillage control.
2.0 Scope
This Standard Operating Procedure is applicable for spillage control of solid & liquid materials in Warehouse to be followed at formulation plants of abc company.
3.0 Responsibility
3.1 Officer/Executive warehouse shall be responsible for handling of re-test materials.
3.2 Head Warehouse is responsible for ensuring the compliance of the SOP.
3.3 Head QA or his designee shall be responsible for implementation and compliance with SOP.
4.0 Abbreviations and Definitions
SOP : Standard Operating Procedure
i.e. : That is
No. : Number
QA : Quality Assurance
WH : Warehouse
ETP : Effluent Treatment Plant
HOD : Head of Department
5.0 Procedure
5.1 Precautions
5.1.1 Do not allow any personal movement in the area where spillages have taken place until it is handled.
5.1.2 Person shall wear personnel protective like Goggles, Hand gloves as a necessary safety precaution.
5.1.3 Always water shall be the first preference to handle the spillages.
5.1.4 Use the method of cleaning as per nature of material.
5.2 Procedure for Solid Spillage Control
5.2.1 Keep disposable mop dipped in water on the area where spillage is occurred.
5.2.2 Collect all disposable material in double poly bag. Close it and label it. Send it to ETP for destruction.
5.2.3 Wipe the area with lint free cloth dipped in water and then wipe once again with dry lint free mop.
5.2.4 Collect mop and used hand gloves into poly bag, close the poly bag and label it.
5.2.5 Send it for destruction to scrap yard.
5.2.6 Mop the area with suitable disinfectant as mention in schedule.
5.2.7 Send the Swab Sample of the area (applicable for Sampling and Dispensing Area).
5.2.8 Only after release of Swab Analysis, start any activity in the area.
5.3 Procedure for liquid spillage
5.3.1 Keep disposable mop dipped in water on the area where spillage is occurred.
5.3.2 In case the spillage can not be handled using water use specific Neutralizing Solution 10% NaOH or 10% NaOCl.
5.3.3 In case of volatile solvents do not switch off the AHU’s.
5.3.4 Mop the surface with lint free cloth dipped in water.
5.3.5 Collect all disposable mops in double poly bag. Close it and label it. Send it to scrap yard for destruction.
5.3.6 Collect mop and hand gloves used for cleaning, into poly bag, close the mouth of the poly bag and label it.
5.3.7 Send it for destruction to scrap yard.
5.3.8 Mop the area with suitable disinfectant as mention in schedule.
5.3.9 Send the Swab Sample of the area (applicable for Sampling and Dispensing Area).
5.3.10 Only after release of swab analysis start any activity in the area.
6.0 Forms and Records
6.1 None
7.0 Distribution
7.1 Master Copy – Documentation Cell (Quality Assurance)
7.2 Controlled Copy – Warehouse Department.
8.0 History
Revision Number | Details For Change |
Reason for Revision |
00 | New SOP | NA |
- process validation protocol for methylcobalamin niacinamide and pyridoxine injection
validation protocol of sterility test
sop for Analytical Method Transfer
Protocol for hold time study of sterile garments
sop for swab sampling for validation of clean surfaces
cleaning validation maco and noel calculation formula
sop for performance qualification for analyst
Sop for Validation report for disinfectant efficacy
Sop for Method validation report for bacterial endotoxin test
Sop for method validation microbiology sterility testing
sop for validation report for preservative efficacy test
sop for Protocol cum report for efficacy qualification of uv light
sop for validation protocol for uv light efficacy of dpb & laf
sop for cleaning validation protocol tablet manufacturing equipment
sop for cleaning validation protocol ointment manufacturing equipmentconcurrent process validation for rabeprazole ec and domperidone sr capsules
sop for Validation for cleaning procedure liquid injection
sop for Validation for cleaning procedure dry powder injection
Preparation Approval Control and Distribution of Master Formula Records
calibration policy for equipment and instruments
evaluation Sampling of Raw Materials questionnaire
training evaluation questionnaire
sop for approval of Contract Parties
sop for Operation and Cleaning of Purified Water Generation System
sop for Storage of Standard Weights
sop for Dispensing of Raw Material
Receipt of Excess RM/PM from Production
sop for Dispatches of Finished Goods
Cleaning of Dispensing and Sampling Area
procedure for cleaning of dispensing tools
Cleaning and Operation of Reverse Laminar Air Flow
Handling of Open-Damaged Containers in Warehouse
sop for Discard of Scrap From Warehouse
Cleaning and Operation of Reverse Laminar Air Flow
sop for Cleaning of High Racks
sop for Issuance of Excess RM/PM to Production
sop for Cleaning of MS Shutter
procedure for handling of rejected materials
sop for Generation of Goods Receipt Note