procedure for Cleaning of laboratory glassware
1.0 OBJECTIVE
1.1 To lay down a procedure for Cleaning of laboratory glassware.
2.0 SCOPE
2.1 This procedure is applicable for Cleaning of laboratory glass ware in Quality control Department
3.0 RESPONSIBILITY
3.1 QC Officer or QC Executive
4.0 ACCOUNTABILITY
4.1 QC Manager
5.0 PROCEDURE
5.1 Preparation of cleaning solutions
5.1.1 For the cleaning of glassware, those are used for chemical analysis special precautions will take place to
avoid any chemical residue in glassware, which may later interfere with the results of chemical analysis.
Following cleaning solutions were used for cleaning of glassware.
5.2 2% Liquid soap solution
5.2.1 Measure 20 ml soap solution and add it to container containing 980 ml of purified water and stir it well.
5.2.2 Record the solution preparation details in glassware cleaning solution preparation record.
5.3 Cleaning glassware
5.3.1 Cleaning of glassware, which has contained hazardous materials, must be solely undertaken by experienced
personnel.
5.3.2 Most new glassware is slightly alkaline in reaction. For precision chemical tests, new glassware should be soaked several hours in acid water (1% solution hydrochloric acid or nitric acid) before washing.
5.3.3 Wash glassware as quickly as possible after use if it is not possible then the articles should be allowed to
soak in water.
5.3.4 For cleaning of glassware such as bottles, flasks, beakers, test tubes, etc use 2% liquid soap solution. For
better results use hot water.
5.3.5 During the washing all parts of the article should be thoroughly scrubbed with a brush selected for the shape
and size of the glassware. Brushes should always be in good condition to avoid any abrasion of the glassware.
5.3.6 Special types of precipitate material may require removal with nitric acid, aqua regia or fuming sulphuric acid.
These are very corrosive substances and should be used only when required.
5.3.7 Before cleaning of glassware remove the labeling of marker pen with the help of IPA or acetone. For plastic
ware do not use acetone for removing marker pen labeling.
5.3.8 It is imperative that all soap detergent and other cleaning fluids be removed from glassware before use. This
is especially important with detergents, slight traces of which will interfere with serological and culture reactions.
5.3.9 After cleaning, thoroughly rinse with tap water ensuring that containers are partly filled with water, shaken
and emptied several times. Finally rinse with purified water.
5.3.10 After cleaning dry the glassware in Hot air oven at 60℃ temperature ± 5℃.
5.3.11 Always protect clean glassware from dust by use of temporary closures or by placing in a dust free cabinet.
6.0 ABBREVIATION
| Abbreviation used | Extended Form |
| SOP | Standard Operating Procedure |
| No. | Number |
sop for Calibration and Maintenance of Laboratory Instruments and Equipment
Disposal of Residual Sample or Left Over Material
sop for for Laboratory Incident
standard operating procedure temperature monitoring
sop for operation of infrared moisture balance
sop for preparation of mobile phase
sop for Preparation and Issuance of Analysis protocol standard
sop of placebo and impurity stock solutions
sop for disposal of residual sample
sop for handling of pharmacopoeial changes
sop for procedure for operation of ultrasonic cleaner
difference between UPLC and HPLC
sop for for Emergency Eyewash and Shower
sop for operation and calibration of total organic carbon analyzers
sop for operation of cobb tester
sop for Operation and calibration of atomic absorption spectrophotometer
sop for Operation and calibration of gas liquid chromatograph
sop for operation of humidity oven
sop for operation and calibration of serological water bath
sop for monitoring of drain trap
sop for destruction of analytical samples after testing and control samples
sop for destruction of used chemicals
Sop for Operation of suction pump
sop for Operation and calibration uv cabinet
sop for Operation and calibration of bulk density apparatus
sop for operation and calibration of shore hardness tester
sop for operation of rub proofness tester
sop for monitoring of purified water
sop for Retesting of packaging materials
sop for Retesting and resampling of raw materials
sop for Control of issuance of record of analysis green sheets
sop for Control of computer passwords
sop for sampling of packaging materials PM
sop for sampling of sterile raw material
sop for sampling of intermediates and finished products
sop for operation and calibration of friability test apparatus
sop for approval and rejection of packaging materials
sop for non conformance of RM PM and finished product
sop for collection storage and disposal of control samples
sop for trend analysis of finished products
sop for Chromatographic practices and system suitability
SOP For Good Laboratory Practices
sop for cleaning and operation of sieve shaker
general specification of packing material cartons
sop for Password for Analytical Instrument and LIMS software
sop for Rounding off numerical analytical results
sop for sampling of bulk and finished product
sop for cleaning of spillage material
sop for Handling of Reference Standard
sop for hplc column maintenance and washing
procedure for sampling and handling of bulk sample
STP for borewell generation point (raw water storage tank)
sop for preparation and standardization of 0.1M Zinc Sulphate
Operation &calibration of analytical balance (dhona)
Operation and Calibration Procedure for Disintegration Test apparatus
sop for preparation and standardization of 1 M Hydrochloric Acid
Preparation and standardization of 0.1 M ceric ammonium sulphate solution
sop for preparation and standardization of 0.05 m iodine solution
validation of volumetric solution 0.1m ammonium thiocyanate
handling of reference standard and preparation of working standard
sop for water sampling and analysis
sop for operation for validation of excel worksheets
sop for stability of volumetric solutions
sop for preparation of raw material in process finish product packing material data sheets
sop for handling of hazardous chemicals
sop for handling of glassware and allocation of identification number
sop for operation cleaning and calibration of bursting strength tester
sop for rounding off the analytical test results
procedure for Analyst Qualification
sop for operation and calibration of dissolution Apparatus
procedure for maintenance of desiccators
sop for for hplc column receipt checking id no and regeneration
safety data sheet for laboratory chemicals
procedure for handling of poisonous chemicals
sop for cleaning of sampling devices
sop for calibration procedure of instruments
sop for specification and standard testing raw material packing material and finished product
procedure for operation and calibration of potentiometric titrator
procedure for operating and calibration of digital hardness tester
procedure for disposal of expired chemicals, reagents and solvents
sop for behavior in quality control department
sop for preparation and standardization 0.1M sodium thiosulphate
sop for preparation and standardization 0.1M Disodium Edetate
preparation and standardization 0.1M Sodium Hydroxide Solution
Preparation and standardization of 0.1M Perchloric acid solution
sop for preparation 0.05M edetate disodium
sop for preparation 0.1M silver nitrate
sop for Operation and Calibration of High Performance Liquid Chromatography
sop for UV & Visible Spectrophotometer
procedure for Cleaning of laboratory glassware
Cleaning of Instrument, Instrument bench and surrounding area of Quality
Safety Precaution in Quality Control Department
Operation & Calibration of Analytical Balance
Calibration of Glassware in Quality Control Department
handling of samples received in Quality Control
Cleaning and Operation of Refrigerator
Operation, Cleaning and Calibration of water bath
Operation & Calibration of Refractometer
Operation and Cleaning of Centrifuge Apparatus
cleaning, operation & calibration of Vernier caliper
Calibration of Fourier Transform Infrared Spectrophotometer (FTIR)
Cleaning and operation of Moisture Analyzer
Cleaning & Operation of Vacuum pump in Quality Control Department
Operation and Calibration of Polarimeter
Cleaning and operation of Magnetic Stirrer
Cleaning Operation and Calibration of Melting Point
Operation Cleaning and Calibration of Muffle Furnance in Quality Control Department
procedure of operation and Cleaning of Sonicator
Operation Cleaning & Calibration of pH meter in Quality Control Department
Entry and Exit in Quality Control Department
