General Test Procedure Acid Soluble Substances

 

 

1. Purpose
   1. This procedure is applicable to all incoming Raw materials.
2. Apparatus
   1. Calibrated balance
   2. Evaporating dish
   3. Sintered glass crucible-G4 & desiccator
3. Reagents
   1. Hydrochloric Acid
4. Procedure
   1. Place a clean and dry evaporating dish in an oven at 105 °C for 15 minutes. Remove it and keep in a desiccator for 15 minutes. Record the weight.
   2. Unless otherwise specified, weigh accurately about 1 g sample in a 100 ml beaker add 25 ml 1N hydrochloric acid or recommended acid solution in the monograph. Boil it for 5 minutes and filter the hot solution through a sintered glass crucible (G4), and wash with 10 ml of hot water.
   3. Collect all the filtrate and transfer to a previously weighed dish as in step (i).
   4. Place the dish on a boiling water bath and continue the heating to the dryness of residue.
   5. Take out the dish and clean the bottom with tissue paper (there should not be any deposition /scaling at the bottom of dish).
   6. Keep the dish in an oven at 105 °C for 30 minutes, remove and place it in a desiccator, allow it to cool for 15 minutes.
   7. Record the weight of dish with residue and calculate the acid soluble substances by formula:

 

 

 

5.  Reference
   1. None
6. Revision History

Revision No.	Details of Changes	Reason for change
00	New GTP	NA

End of Document

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