Site icon Pharma Dekho

Procedure for housekeeping of general area cleaning 

 

Procedure for housekeeping of general area cleaning  

 

1.0 OBJECTIVE
1.1 To ensure that hygienic and housekeeping of general area maintained.
2.0 SCOPE
2.1 This procedure applies to the manufacturing facilities ……..
3.0 RESPONSIBILITY
3.1 Officer – H.R. and Administration
4.0 ACCOUNTABILITY
4.1 Head – H.R. and Administration
5.0 REFERENCE(S)
5.1 In- house.
6.0 ENVIORMENT, HEALTH & SAFETY
6.1 Put on face mask and hand gloves while preparing the disinfectants.
6.2 Wash the plastic carboy thoroughly with water before preparing the disinfectants
6.3 As phenol is corrosive, thus handle carefully.
7.0 PROCEDURE
7.1 De-dusting with Nylon broom: procedure and schedule attached.
7.2 Dry moping: procedure and schedule attached.
7.3 Wet moping with Teepol detergent and disinfectant solution : procedure and schedule attached
7.3.1 Cleaning of Change Rooms

Area

Frequency

Intended Days

Method of Cleaning

Change Rooms
Ceiling & Walls

(Above 6 ft. Height )

Manufacturing Area

 

Once in each shift

(Before Starting of shift or during Product Change Over  in the specified Area)

Daily

 

 

Dry mopping followed by wet Mopping with scheduled Disinfectant.
Walls

( Up to 6 ft. height )

Manufacturing Area

Minimum Twice Per shift

(before starting of shift, during lunch break & during Shift end)

 

Daily Dry mopping followed by wet Mopping with Disinfectant solution scheduled for the day.

Mopping Must be done after it’s cleaning.

Floor

 

 

 

Minimum Twice Per shift

(before starting of shift, during lunch break & during Shift end)

Mopping Must be done after   cleaning of floor.

Daily   i. De-dusting with clean cloth.

ii. Wet Mopping using

disinfectant solution     Scheduled for the day.

Glass Windows & Doors Once Daily Daily Use Colin and Wipe with lint free cloth
Light Fixtures Weekly Saturday evening Dry Mopping.
  Exhaust Weekly Saturday, Evening Dry mopping following by wet mopping with Disinfectant Solution
Sinks Once Per shift Daily Scrubbing jet washing and mopping with disinfectant.

 



 

Area

Frequency

Intended Days

Method of Cleaning

Quality Assurance
Ceiling  & Walls

(Above 6 ft. Height )

Other than Manufacturing Area

Twice in a week

         

Monday, Friday Dry mopping
Walls

(Up to 6 ft. Height)

Other than Manufacturing Area

Once in each Shift Daily Dry mopping
Glass Windows & Doors Once Daily Daily Use Colin and Wipe with lint free cloth
Light Fixtures Weekly Saturday evening Dry Mopping.
Fan & Exhaust Weekly Saturday, Evening Dry mopping following by wet mopping with Disinfectant Solution
Furniture

 

Once Per Shift Daily Cleaning of surface with dry mop and damp mop with disinfectant Solution
Racks & Almirah Once Per shift Daily Cleaning of surface with dry mop and damp mop with disinfectant Solution
Floor Twice Daily

Morning & Evening

Daily i.         De-dusting with Nylon  broom

ii.   Wet moping using 0.5% w/v       solution of Detergent in water.

iii.  Mopping by using scheduled   disinfectant solution  in water

Other Surrounding Areas Once per Shift Daily Cleaning of surface with dry mop and damp mop with disinfectant solution

7.3.2 Cleaning of Toilets

Area

Frequency

Intended Days

Method of Cleaning

LAVATORY Thrice per Shift Daily Washing through running water

Scrubbing  with brush using cleaning powder and finally washing with

Phenyl solution  10% (Approx.)

Other Surrounding Areas Thrice per Shift Daily Washing through running water

Scrubbing  with brush using cleaning powder and finally washing with

Phenyl solution  10% (Approx.)

7.3.3 Surroundings

Area

Frequency

Intended Days

Method of Cleaning

Road Twice Daily

Morning & evening

Daily Stick broom
Weekly Monday Washing Through running water

 

7.4 Schedule for Using Disinfectant & Cleaning agents.

Disinfectant Solution Code Schedule Date
Savlon A 1 4 7 10 13 16 19 22 25 28 31
Dettol B 2 5 8 11 14 17 20 23 26 29  
Actall C 3 6 9 12 15 18 21 24 27 30  
Teepol D Daily

7.5 Method for Preparation of “Savlon”( 2.5 % v/v Solution) disinfectant solution

Preparation of Savlon Solution Storage Shelf life
Savlon 250 ml. In plastic carboy 24 Hour
Water (PW/WFI) 9.750 Ltr.

Take 250 ml of Savlon in a plastic carboy and makeup volume up to 10.0 Ltr. Water (PW/WFI) and stir well

7.6 Method for Preparation of “Dettol” (2.5 % v/v Solution) disinfectant solution:

Preparation of Dettol Solution Storage Shelf life
Dettol  250 ml. In plastic carboy 24 Hour
Water (PW/WFI)  9.750 Ltr.
Preparation of Actall Solution Storage Shelf life
Actall  250 ml. In plastic carboy 24 Hour
Water (PW/WFI)  9.750 Ltr.

7.8 Method for Preparation of “Teepol”(0.1 % v/v Solution) Solution

Preparation of Teepol solution Storage Shelf life
Teepol 10ml. In plastic carboy 24 Hour
Water (PW/WFI) 9.990 Ltr.

Take 10 ml of Teepol solution in a plastic carboy and makeup volume up to 10.0 Ltr. Water (PW/WFI) and stir well.
7.9 Record the Disinfectant Solution Preparation details in “Disinfectant Solution Preparation Record”, in Annexure – I Format No.
7.10 Record the Cleaning & Sanitation details in “Cleaning & Sanitation Record”, Annexure-II Format No.
7.11 Cleaning details related with entire lavatory area of a Block will be recorded daily in a single separate format. Format attached as Annexure-III Format No.
8.0 HISTORY

SOP NO. REASON FOR CHANGE REVISION NUMBER CHANGE CONTROL NUMBER EFFECTIVE DATE
  New SOP 00 NA  

NA                          :               Not Applicable

No.                          :               Number

SOP                        :               Standard Operating Procedure

10.0 ANNEXURE

Annexure No. Title of Annexure Format No. of Annexure
Annexure–I Disinfectant Solution Preparation Record  
Annexure–II Cleaning & Sanitation Record  
Annexure–III Cleaning & Sanitation Record (Lavatory Area)  
Annexure–IV Disinfectant Solution Label  
Annexure–V Cleaning Solution Label  

 

SOP FOR BATCH MANUFACTURING

sop for placebo batch

sop for Cleaning of Ampoule Filling and Sealing Machine

sop for Fogging in Sterile and Non Sterile Area

sop for for Filtration of Bulk Solution

sop for fumigation in production area

sop for post cleaning after media fill

sop for cip of mixing vessel mixing mobile vessel and holding vessel

sop for De-Bagging of Three Piece Vial Dropper Caps

sop for calibration and verification of check weigher

sop for Batch number and Manufacturing and Expiry Date Coding System

sop for Sanitization of Seals

standard operating procedure machine history file

sop for operation and cleaning of Hand coder

sop for Cleaning and Handling and Silicone Tubes

sop on operation and cleaning of coating pan

sop for Operation of cleaning of pipe lines

Sop for equipment assembly

sop for operation of capsule loading machine semi automatic

sop for Machine operation capsule inspection and polishing machine

Sop for issue of material

Sop batch demarcation and batch coding

sop for material receipts

sop for monitoring of reprocessing of products

sop for in-process control on liquids orals

sop for in process controls on tablets capsules packaging line

sop for Issuance retrieval and destruction of BMR and analytical records

sop for in process controls during granulation compression coating inspection

sop for Cleaning of Blister packing machine

sop for for charge hand over between the shifts

Performance requalification report of visual inspectors

sop for Cleaning and operation of ROPP caps inspection table

sop for usage and destruction of filter pad and cartridge filter

sop for cleaning and storage of transfer pipe

sop for Cleaning and operation of labeling machine

Cleaning and operation of the mono block filling and sealing machine

sop for Cleaning and operation of empty bottle inspection table

sop for Cleaning and operation of filter press

sop for cleaning and operation of liquid transfer pump and line

sop for cleaning and operation of storage vessels

sop for cleaning and operation of sugar syrup manufacturing vessel

sop for cleaning issuance and retrieval of accessories and change parts

sop for Cleaning and operation of visual inspection conveyor belt

sop for Fire Fighting

sop for Security persons

Sop for first aid

Exit mobile version