sop for cleaning and operation of liquid transfer pump and line
1.0 OBJECTIVE
1.1 To describe the cleaning & operation of cleaning & operation of liquid transfer pump and line.
2.0 SCOPE
2.1 This procedure is applicable for liquid transfer pump and line present in the production liquid department.
3.0 RESPONSIBILITY
3.1 Operator – To perform the procedure.
3.2 Officer production- To ensure that the operation is being performed in compliance with the
SOP.
3.3 IPQA person – To ensure in-process checks, and counter check that the
Compliance is in line with SOP.
4.0 ACCOUNTABILITY
4.1 Department Head
5.0 PROCEDURE
5.1 Cleaning: Type A procedure (Batch to Batch Cleaning)
5.1.1 Ensure all the material is removed from the equipment.
5.1.2 Remove the product status label and affix ‘To be cleaned’ status label as per sop over the equipment.
5.1.3 Type A cleaning applicable for batch to batch cleaning of same strength, color, and flavor and continuous five batches.
5.1.4 Type A cleaning applicable for shift end cleaning and continue five batches.
5.1.5 Check and ensure the cleanliness and availability of accessories used for cleaning Nylon brush, Nylon scrubber, Lint free cloth, Gloves.
5.1.6 Take 50 liter potable water in S.S container and connect the transfer pump with line.
5.1.7 Start transfer pump and drain used potable water.
5.1.8 Repeat this process with purified water.
5.2 Cleaning: Type B procedure
5.2.1 Ensure all the material is removed from the equipment.
5.2.2 Remove the product status label and affix ‘To be cleaned’ status label as per sop over the equipment.
5.2.3 Check and ensure the cleanliness and availability of accessories used for cleaning Nylon brush, Nylon scrubber, Lint free cloth, Gloves.
5.2.4 After continue five batches, Type B cleaning should be performed.
5.2.5 Spray potable water on the outer surface of the filter press to remove the adhered material.
5.2.6 Take 50-liter potable water in S.S container and connect the transfer pump with line.
5.2.7 Start transfer pump and drain used potable water.
5.2.8 Repeat this process with 50-liter purified water.
5.2.9 Finally take 50-liter hot purified water (80 to 85oc) and repeat above process.
5.2.10 Inform IPQA to collect rinse/swab sample for QC to analysis.
5.3 OPERATION
5.3.1 Push green button to start the operation.
5.3.2 Push red button to stop the operation.
5.3.3 In case of AODD pump connect with compressed air line to start the operation. And To stop disconnect the compressed air supply.
6.0 TRAINING
6.1 Trainer: Department Head.
6.2 Trainee: Production, Quality Assurance and Operator person.
6.3 Period: one hour or as per required.
7.0 DISTRIBUTION
7.1 One set of Master copy and one set of Controlled copy submit the QA department.
8.0 ENCLOSURES
8.1 NIL
9.0 ABBREVIATIONS
9.1 IPQA : In-process Quality assurance
9.2 BMR : Batch manufacturing record.
9.3 SOP : Standard operating Procedure.
9.4 QC : Quality Control
9.5 AODD PUMP : Air Operated Double Diaphragm Pump
10.0 DOCUMENT CHANGE HISTORY
| Revision | Reason for revision | Effective Date
|
| 00 | NEW SOP |
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